The Portuguese player scored three of the English champions in front Watford in an 8-0 rout.
Manchester City, who had lost on the last day of their visit to Norwich City, responded impressively by beating Watford 8-0 at their stadium on a 3-goal afternoon with Bernardo Silva.
Bernado Silva, who started and scored three goals in the reception of the hornets, made his first hat-trick of his career.
The other goals were scored by David Silva, Sergio Aguero, Riyad Mahrez, Nicolás Otamendi and Kevin de Bruyne.
João Cancelo also contributed to the team, surrendering Kyle Walker in the 54th minute when City won 5-0.
Manchester City has 13 points, two fewer than Liverpool, who face Chelsea at Stamford Bridge on Sunday. As for Watford, it is increasingly last, with just two points earned in six rounds.